Combining Artvigil 150 with caffeine can increase the risk of overstimulation, as both substances are central nervous system stimulants. While Artvigil 150mg helps promote wakefulness and cognitive function, caffeine is commonly consumed to boost alertness. Using them together may intensify side effects such as jitteriness, anxiety, increased heart rate, and insomnia. It's important to monitor how your body reacts when combining these substances, and if you experience any discomfort or unusual symptoms, it's wise to reduce or avoid caffeine intake while using Artvigil. Always consult with a healthcare provider before combining stimulants.